|Private Banking vs. Public Banking
|Individual's Rights to Cord Blood Stem Cells
||Client owns the cells; full rights are preserved.
||None. Donor relinquishes ownership upon donation.
|Cost to Donor
||Client pays a one-time processing fee and annual storage fees.
||No cost. There is no cost to the donor, nor is a fee paid for the donation.
||The collection for family banking can occur virtually anywhere.
||Limited access to collection services. Public banks only collect cord blood at a limited number of locations.
|Access to One's Cells
||Virtually assured. Clients and their physicians control the use of their individual family’s stem cells.
||Not likely due to the following factors: 1) Approximately 70% of cord blood donated to public banks is discarded for not meeting process and storage criteria. Therefore, there is a reasonably high likelihood that a specific sample will not be in the public bank's inventory to begin with.
2) Public banks release cells when a good match is identified with an unrelated recipient. This is one more reason that the cells may not be in the public bank’s inventory.
3) Once the cells have been donated to a public bank, most public banks’ consent forms do not provide a family the ability to retrieve them for private use when there is a need.
|Cost to Retrieve Cells for Transplant
||Quorus Technology: None.
||The current average cost is $35,000 per public cord blood unit, included as part of the hospital bill.
|Availability of Specimen for Timely Transplants
||Immediately available, once a match is confirmed.
||Search and match process may take weeks or months; ultimately, a match may not be located.
||Using stem cells from a related donor significantly lowers the incidence of Graft vs. Host Disease (GVHD) where the transplanted cells react against tissues in the recipient and can be fatal.
||Graft vs. Host Disease (GVHD) is estimated to occur in 60-80 percent of transplants where the donor and recipient are not related.
|Opportunity for Matching
||Autologous (self): 100% Match is guaranteed.
Siblings: 1-in-4 chance of a perfect match, 39% chance of a transplant-acceptable match.
|Varies. It can be especially difficult to obtain matched cells in public banks for ethnic minorities and individuals of mixed ethnicity.
|Future Therapeutic Opportunities
||Family banking creates the opportunity for use of one's own and a family member’s cells for future cellular therapies to potentially treat stroke, heart attack, diabetes, and a range of other serious medical conditions.
||Uncertain. Donating cells to a public bank makes it less likely that the cells will be available to the donor for use in future therapies.