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The PrepaCyte-CB® Processing System is intended for use in cell processing laboratories to process and store total nucleated cells (TNC) from human umbilical cord blood, prior to banking. The device is composed of three integrally-attached processing and storage containers (or a single processing container) with separation media.

PrepaCyte-CB yields the highest number of colony-forming units (CFUs) and provides the greatest reduction in red blood cell (RBC) contamination over other processing methods.





CFU Recovery % Post Thaw1 




RBC Depletion % 




The Benefits of PrepaCyte-CB

PrepaCyte-CB compared to other processing methods

  • PrepaCyte-CB yields the highest number of colony-forming units (CFUs) which is currently the most accurate measurement used to determine stem cell potency and the potential for stem cell engraftment.4,6,7 
  • PrepaCyte-CB recovers the greatest percentage of CD34+ stem cells from human umbilical cord blood.4
  • PrepaCyte-CB is the most flexible method, the only processing type where TNC and CD 34+ recovery is not affected by the initial volume of the collected unit, leaving desired TNCs and stem cells unmodified and unaffected during cord blood processing.4
  • PrepaCyte-CB processed samples have a significantly greater clonogenic potential than all current methods.4
  • PrepaCyte-CB processed cord blood units engraft the fastest. When evaluating both the probability of and the time to patient neutrophil recovery, there is a significant difference between the groups with respect to median time to recover. The PrepaCyte CB cohort had a median time of 15 days as compared to 21 days for the Hespan group.3, 5

Benefits for the laboratory 

  • PrepaCyte-CB is intuitive and easy-to-use, permitting rapid implementation within new and existing cord blood banks.
  • PrepaCyte-CB allows batch processing and reduces "hands on" staff time. A number of cord blood banks have realized a time-savings of 50 minutes per cord blood unit using PrepaCyte-CB compared to its previous hetastarch processing method.
  • PrepaCyte-CB requires no costly capital equipment or maintenance fees. Only a standard laboratory centrifuge is required to concentrate desired cells after separation.

Additional features of PrepaCyte-CB's processing method 

  • FDA 510K approved product: PrepaCyte-CB is manufactured under FDA current Good Manufacturing Practices (cGMP)
  • Completely closed system: greatly reduces the chance for contamination during processing. 
  • Sterile device composed of three integrally attached bags. Of the three bags, one comes pre-filled with the PrepaCyte-CB separation solution, one is empty and one storage bag is for cryopreservation of the collected cells. The system’s interconnected, closed-bag set limits cell manipulation and helps minimize environmental contamination and identification errors.
  • PrepaCyte-CB’s bag set and separation solution are shown to be non-toxic.
Caution: Federal Law restricts this device to sale by or on the order of a licensed practitioner